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Cell > Antibody Screening Cell
MeDiPro Antibody Screening Cell
Summary and principle:

A MeDiPro Antibody Screening Cell kit includes three bottles of screening cell (Ⅰ.Ⅱ.Ⅲ.) and two bottles of ABO reverse typing cell (A cell and B cell). Antibody screening cell are 3% suspensions of group O cells differing in antigenic configuration for use in antibody screening, and are selected to enable detection of most clinically significant blood antibodies. The antigen typings of each donor are provided on the antigenic constitution matrix that accompanies each product. Antibodies react with red blood cells processing the corresponding antigenic determinant which is antibodies and erythrocytes forming agglutination.

ABO reverse typing cells are designed for routine ABO blood grouping by detection of ABO blood group antibodies in serum or plasma. Ordinarily, individuals possess antibodies directed toward the A or B antigen absent from their own red cells. This allows the serum of an individual to be tested with known A and B red cells to demonstrate the presence or absence of the ABO blood group antibodies anti-A, anti-B and/or anti-A,B (reverse grouping). Any discrepancies found between the forward and reverse grouping results may be due to unusual genetic blood group variants and must be resolved prior to the ABO Group being reported or used for transfusion.

Advantage:

The antibody screening cells are carefully selected to express the antigens associated with the most clinically relevant antibodies, especially the Mia and Dia antigens. The two blood cell antigens express in all Caucasian without anti- Mia or/and Dia antibodies, but different in Taiwan people. MeDiPro Antibody Screening Cell could be utilized to screen out who carries anti- Mia or/and Dia antibodies.

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